Who should i start11/9/2023 It is not the right choice for people who may be exposed to HIV frequently - for example, if you often have sex without a condom with a partner who is HIV-positive. Can I take PEP every time I have unprotected sex? So it's important to tell your provider about any other medicines that you take. PEP medicines may also interact with other medicines that a person is taking (called a drug interaction). If you are taking PEP, tell your provider if you have a side effect that bothers you or that does not go away. The side effects are usually not serious and often get better over time. Some people taking PEP may have side effects, like nausea. You will have to see your provider at certain times during and after taking the PEP, so you can have an HIV screening test and other testing. You need to take the PEP medicines every day for 28 days. The sooner you start it, the better every hour counts. PEP must be started within 72 hours (3 days) after a possible exposure to HIV. When should I start PEP and how long do I need to take it? PEP may also be given to a health care worker after a possible exposure to HIV at work, for example, from a needlestick injury. Your provider or emergency room doctor will help to decide whether PEP is right for you.
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